The Best Toothbrush Replacement Heads 2025

1. iO Series Ultimate Clean Replacement Brush Head for Oral-B iO Series Electric Toothbrushes (2-Count) - White

Sonic technology; Smartimer; easy-start feature; rubber grip; 2-color charge indicator; rechargeable battery; up to 10 days of battery life

Keep your teeth clean and healthy with this two-pack of Oral-B Ultimate Clean replacement brush heads. The dual-length tufted bristles reach in between teeth for a deep clean, while the round head design covers each tooth for effective plaque removal. These Oral-B Ultimate Clean replacement brush heads are compatible with Oral-B iO series handles for easy use.

2. iO Series Ultimate Clean Replacement Brush Head for Oral-B iO Series Electric Toothbrushes (2-Count) - Black

Sonic technology; Smartimer; easy-start feature; rubber grip; 2-color charge indicator; rechargeable battery; up to 10 days of battery life

Stay on top of your dental hygiene with this two-pack of Oral-B iO Ultimate Clean replacement brush heads. The round brush head envelopes each tooth for effective plaque removal, while the dual-length bristles reach deep in between teeth to remove food debris. These Oral-B iO Ultimate Clean replacement brush heads are compatible with Oral-B iO electric toothbrushes for seamless use.

3. Philips Sonicare - Simply Clean Brush Heads (5-Pack) - White

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Maintain healthy brushing habits with these Philips Sonicare SimplyClean HX6015/03 toothbrush heads, which feature a contoured design to fit your mouth and clean hard-to-reach places. Snap-on attachment allows easy use with select Sonicare toothbrushes.

4. Philips Sonicare - Premium Plaque Control Brush Heads (4-Pack) - Black

Proprietary brushless motor; Smart Percussive Therapy; Bluetooth connectivity; OLED screen; delivers up to 60 lbs. of no-stall force; 6 interchangeable attachments; battery-powered

Clean and polish those pearly whites with these Philips Sonicare Premium Clean replacement brush heads. This four-pack of brush heads maximizes the sonic motion of your compatible brush for more effective brushing. The design of these Philips Sonicare Premium Clean replacement brush heads provides four times more surface contact with your teeth for optimal cleaning and enhanced oral health.

5. Philips Sonicare - DiamondClean Replacement Toothbrush Heads (4-pack) - White

FLT5800 HEPA Replacement Filter

Stock up on replacements with this 4-pack of Phillips Sonicare toothbrush heads. The diamond-shaped bristles gently clean your teeth, and the sonic motion gets rid of seven times more plaque than manual brushing to keep your smile bright. These Phillips Sonicare toothbrush heads are compatible with all Sonicare click-on models to keep the whole family supplied.

6. Philips Sonicare - DiamondClean Replacement Toothbrush Heads (4-pack) - Black

FLT5800 HEPA Replacement Filter

Give your DiamondClean toothbrush a facelift with this four-pack of Philips Sonicare brush heads. They have diamond-shaped bristles to make teeth appear whiter after a week of use, and they gently remove seven times more plaque compared to a manual toothbrush. These black Philips Sonicare brush heads are compatible with BrushSync models that offer visual replacement reminders.

7. Philips Sonicare - Optimal Plaque Control Replacement Toothbrush Heads (3-pack) - White

Proprietary brushless motor; Smart Percussive Therapy; Bluetooth connectivity; OLED screen; delivers up to 60 lbs. of no-stall force; 6 interchangeable attachments; battery-powered

Maintain your dental hygiene routine with this 3-pack of Philips Sonicare replacement toothbrush heads. The concave design conforms to teeth to provide maximum coverage, and BrushSync mode-pairing ensures optimal plaque removal. The bristles on these Philips Sonicare replacement toothbrush heads fade to alert you when it's time to replace them.

8. Philips Sonicare - Philips One by Sonicare 2pk Brush Heads - Shadow Black

Philips Sonicare 4100 Power Toothbrush, Deep Pink HX3681/26 National

Philips One by Sonicare 2pk Brush Heads, Black BH1022/06

9. Philips Sonicare - Philips One by Sonicare 2pk Brush Heads - Midnight Navy Blue

Philips Sonicare 4100 Power Toothbrush, Deep Pink HX3681/26 National

Philips One by Sonicare 2pk Brush Heads, Midnight BH1022/04

10. iO Series Gentle Care Replacement Brush Head for Oral-B iO Series Electric Toothbrushes (2-Count) - White

Sonic technology; Smartimer; easy-start feature; rubber grip; 2-color charge indicator; rechargeable battery; up to 10 days of battery life

Get a thorough, professional clean with this two-pack of Oral-B iO Gentle Care replacement brush heads. The unique round head helps you get into hard-to-reach areas, while the optimized bristles deliver a powerful performance that's gentle on the gums and enamel. These Oral-B iO Gentle Care replacement brush heads are compatible with Oral-B iO toothbrush handles for seamless replacement.