Updated On July 29th, 2025
Looking for the best Cough & Cold Must Haves? You aren't short of choices in 2022. The difficult bit is deciding the best Cough & Cold Must Haves for you, but luckily that's where we can help. Based on testing out in the field with reviews, sells etc, we've created this ranked list of the finest Cough & Cold Must Haves.
Rank | Product Name | Score | |
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1 |
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Alka-Seltzer Plus Night Maximum Strength Cold & Flu, Liquid Gel, 20ct
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94.09%
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2 |
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Alka-Seltzer Plus Severe Sinus Congestion Allergy & Cough, Liquid Gels, 20 ct
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94%
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3 |
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Alka Seltzer Plus, Day & Night Severe Sinus Congestion & Cough Maximum Strength, 20 ct
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94%
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4 |
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Alka-Seltzer Plus Day Severe Cold & Flu, Honey Lemon Fast Relief Mix-In Packets, 6 Count
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94%
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5 |
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Alka-Seltzer Plus Maximum Strength Cold & Flu Medicine, Day, Powermax Liquid Gels, 16 Count
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94%
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6 |
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Alka-Seltzer Plus Maximum Strength Cold & Flu Medicine, Day + Night, Liquid Gels, 20 Count
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92%
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7 |
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Alka-Seltzer Plus Maximum Strength Cold & Cough Liquid Gels, 20 ct
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92%
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8 |
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Alka-Seltzer Plus Night Severe Cold & Flu, Honey Lemon Fast Relief Mix-In Packets, 6 Count
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92%
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9 |
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Alka-Seltzer Plus Maximum Strength Cold & Cough, Liquid Gel, 10ct
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90%
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10 |
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Alka-Seltzer Plus Maximum Strength Cold & Cough, Liquid Gel, 40ct
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40%
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Our Score
When nighttime cold and flu symptoms get in the way of the rest you need, reach for the fast-acting, effective power of Alka-Seltzer Plus Maximum Strength* Night Liquid Gels. No other cold and flu medicine relieves more symptoms: Nasal Congestion, Headache & Body Ache, Cough, Sore Throat, Fever & Runny Nose. *Based on 4 hour dosing.
Alka-Seltzer Plus Maximum Strength Cold & Flu Night Liquid Gels, 20ct: Based on active ingredients, no other cold and flu medicine temporarily relieves more symptoms including: nasal congestion, headache & body ache, cough, sore throat, fever, and runny nose. Nighttime product Package contains 20 liquid gels, 1 dose (2 liquid gels) Maximum strength without a prescription Use as directed
Our Score
When allergies act up, your day may come to a standstill, especially when you're dealing with many symptoms, including a cough. Reach for Alka-Seltzer Plus Maximum Strength* Severe Sinus, Allergy & Cough Liquid Gels for fast-acting, effective relief from: Sinus Congestion, Sinus Pressure, Headache & Pain, Runny Nose, Sneezing, Itchy, Watery Eyes & Cough. *Based on 4 hour dosing.
Alka-Seltzer Plus Maximum Strength Severe Sinus, Allergy & Cough Liquid Gels, 20ct: Provides temporary relief from sinus congestion, sinus pressure, headache & pain, runny nose, sneezing, itchy watery eyes, and cough Temporary relief from your worst allergy symptoms Package contains 20 liquid gels, 1 dose (2 liquid gels) Maximum strength without a prescription Use as directed
Our Score
Maybe it starts with the sniffles, a headache and a little sinus pressure. Before you know it, you're battling multiple symptoms during the day and not getting the rest you need at night. Reach for Alka-Seltzer Plus Maximum Strength* Severe Sinus Congestion & Cough Day & Night Liquid Gels. In one convenient package you get: Daytime relief from:, Nasal & Sinus Congestion, Sinus Pressure, Headache, Body Ache & Cough and Nighttime relief from: Headache & Pain, Runny Nose, Sneezing, Nasal & Sinus Congestion, Sinus Pressure & Cough. *Based on 4 hour dosing.
Alka-Seltzer Plus Maximum Strength Severe Sinus Congestion & Cough Day + Night Liquid Gels, 20ct: Provides temporary daytime relief from nasal & sinus congestion, sinus pressure, headache, body ache, and cough. Provides temporary nighttime relief from headache & pain, runny nose, sneezing, nasal & sinus congestion, sinus pressure, and cough. Daytime and nighttime medication in one convenient package Package contains 20 liquid gels, 1 dose (2 liquid gels) Use as directed
Our Score
The viruses that cause cold and flu symptoms have a way of ambushing you at the worst possible time. That makes choosing the right cold and flu medicine important. Reach for the soothing hot drink mix with lemon zest flavor, that delivers daytime relief without making you drowsy– and still gives you effective relief from: Nasal Congestion, Headache, Sore Throat, Body Ache, Cough, Mucus, Chest Congestion & Fever
Alka-Seltzer Plus Severe Cold & Flu Day Honey Lemon Mix-In Packets, 6ct: Provides temporary relief from nasal congestion, headache, sore throat, body ache, cough, mucus, chest congestion, and fever Non-drowsy Package contains 6 mix-in packets, 1 dose (1 packet) Soothing hot mix drink with honey lemon flavor that requires use of water Use as directed
Our Score
Colds don’t care about the busy day you’ve got planned, and the distracting symptoms at every turn aren’t exactly timed either. With Alka-Seltzer Plus Maximum Strength Day Cold & Flu PowerMax Gels you get concentrated power in a 25% smaller pill* to help take back your day from: Sore Throat, Nasal Congestion, Cough, Sinus Pressure, Fever, Headache & Body Ache
Alka-Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels, 16 Count Alka-Seltzer Plus Maximum Strength Cold & Flu Power Max Gels Day, 16 Liquid Gels: Alka-Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels have a concentrated formula in a smaller liquid gel so it's easier to swallow One dose provides 4 hour day time relief of cough, nasal congestion, headache & body ache, sore throat, and sinus pressure Alka-Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels contain a pain reliever, fever reducer, cough suppressant, and nasal decongestant Temporarily relieves these symptoms due to a cold or flu: Minor aches and pains, cough, headache, sore throat, nasal and sinus congestion, & temporarily reduces fever PowerMax Gels do not have to be taken with meals
Our Score
When you need daytime relief from your cold or flu symptoms – and a restful night so you can tackle the next day – turn to Alka-Seltzer Plus Maximum Strength* Day & Night Cold & Flu Liquid Gels for fast, effective relief. In one convenient package you get: Daytime cold and flu symptom relief from: Nasal Congestion, Cough, Headache & Body Ache, Sore Throat, Sinus Pressure & Fever and Nighttime cold and flu medicine for relief from: Runny Nose, Nasal Congestion, Cough, Headache & Body Ache, Sore Throat & Fever. *Based on 4 hour dosing.
Provides temporary daytime relief from nasal congestion, cough, headache & body ache, sore throat, sinus pressure, and fever Provides temporary nighttime relief from runny nose, nasal congestion, cough, headache & body ache, sore throat, and fever Daytime and nighttime medication in one convenient package Package contains 20 liquid gels, 1 dose (2 liquid gels) Use as directed
Our Score
Colds always seem to come at you with everything they've got. And when you need cold symptom and cough relief that's fast, so you can to get back to your busy life, no other cold medication relieves more symptoms than our Maximum Strength* Cold and Cough Liquid Gels. Get relief from: Cough, Nasal Congestion, Runny Nose, Headache & Body Ache, and Sinus Pressure. *Based on 4 hour dosing.
Alka-Seltzer Plus Cold & Cough Liquid Gels, 20 ct: Based on active ingredients, no other cold medication temporarily relieves more symptoms including: cough, nasal congestion, runny nose, headache & body ache, and sinus pressure. Maximum strength medicine without a prescription Comes in Liquid Gel form Use as directed 20 count
Our Score
Whether you “caught a bug” from a friend, loved one, coworker or perfect stranger, it's good to know Alka-Seltzer Plus is always your ally when it comes to nighttime cold and flu symptom relief. Reach for the fast-acting, Alka-Setlzer Plus Severe Cold & Flu Night to tackle your worst cold or flu symptoms so you can get the rest you need. This comforting drink mix with honey lemon zest flavor relieves your worst cold & flu symptoms: Nasal Congestion, Headache & Body Ache, Runny Nose, Sore Throat, Cough & Fever
Alka-Seltzer Plus Severe Cold & Flu Night Honey Lemon Mix-In Packets, 6ct: Provides temporary nighttime relief from nasal congestion, headache & body ache, runny nose, sore throat, cough, and fever Nighttime product Package contains 6 mix-in packets, 1 dose (1 packet) Soothing hot mix drink with honey lemon flavor that requires use of water Use as directed
Our Score
Colds always seem to come at you with everything they've got. And when you need cold symptom and cough relief that's fast, so you can to get back to your busy life, no other cold medication relieves more symptoms than our Maximum Strength* Cold and Cough Liquid Gels. Get relief from: Cough, Nasal Congestion, Runny Nose, Headache & Body Ache, and Sinus Pressure *Based on 4 hour dosing.
Alka-Seltzer Plus Maximum Strength Cold & Cough, Liquid Gel, 10ct: Based on active ingredients, no other cold medication temporarily relieves more symptoms including: cough, nasal congestion, runny nose, headache & body ache, and sinus pressure. Comes in Liquid Gel form Maximum strength without a prescription Use as directed 10 count
Our Score
Colds always seem to come at you with everything they've got. And when you need cold symptom and cough relief that's fast, so you can to get back to your busy life, no other cold medication relieves more symptoms than our Maximum Strength* Cold and Cough Liquid Gels. Get relief from: Cough, Nasal Congestion, Runny Nose, Headache & Body Ache, Sinus Pressure.*Based on 4 hour dosing.
Alka-Seltzer Plus Maximum Strength Cold & Cough, Liquid Gel, 40ct: No other cold medication relieves more symptoms including: cough, nasal congestion, runny nose, headache & body ache, and sinus pressure.**Based on active ingredients. 40 count Comes in Liquid Gel form Maximum strength without a prescription Use as directed