The Best Giant Stuffed Animals 2025

1. GIANTmicrobes Plush - T4 (T4-Bacteriophage)

GIANTmicrobes Plush - T4 (T4-Bacteriophage) These Giant Microbes Dolls are a Million times their Actual Size!GIANT microbes are health and science products for humorous, educational, collectible, and Smart fun!Products include printed cards with fun fascinating facts.Unique gifts for students, scientists, teachers, health professionals & anyone with a healthy sense of humor!All About the T4 (T4-Bacteriophage) FACTS: T4-bacteriophage may look like something out of a science fiction movie, but if you’re an E. coli bacteria, it is the stuff of your nightmares. This real-life microscopic monster isn’t just hiding under your bed; it’s hunting you, feeling for you with its six deadly feet. When they finally touch your skin and know that you’re there, they grip onto your flesh like talons. Paralyzed with fear, you wait and watch as a tremendous, tusk-like stinger stabs you mercilessly through the middle. Writhing in pain, you feel your predator’s deoxyribonucleic acid (DNA) being injected slowly, menacingly into your very being! You try to resist, of course, but it is futile: your contaminated body starts to grow new copies of the malevolent abomination that has corrupted your soul. In less than an hour, a legion of fiends is swarming inside you. They grow and grow and grow until you are broken, until finally you explode, disappearing into a void of nothingness. By day, T4 has played important roles in a number of scientifically significant experiments. It has hobnobbed with Nobel-prize winning scientists, and has whispered some of the secrets of mutation-genetics to them. It has advanced our understanding of viral infection, and may someday help to control pathogenic bacteria. But don’t let the cool, scientific demeanor fool you. T4 always has one eye on the horizon, watching for the sun to set, waiting for the hunt to begin.

GIANTmicrobes T4 Bacteriophage Recommended Age: 3 Year & Up Recommended Age: 3 Year & Up Plush Toy Entity: Bacteria Plush Toy Entity: Bacteria Age Group: Child/Youth/Adult Gender: Unisex Age Group: Child/Youth/Adult Gender: Unisex

2. Melissa & Doug Giant Giraffe - Lifelike Plush Stuffed Animal (over 4 feet tall)

You don't have to be a kid to love Melissa & Doug's iconic giraffe plush toy. Over four feet tall, this gentle giant brings a touch of the exotic into any environment. The plush giraffe is the perfect accessory in a baby's nursery, and is a great addition to any decor! People of all ages love its presence and charm, whether it's in the living room, playroom, or store front. The giraffe has been crafted with attention to realistic details, and features excellent quality construction. There are so many reasons that this adorable giraffe easy to love!

Awe-inspiring lifelike plush giraffe with beautiful markings, realistic details, and a strong interior structure stands an impressive 4 feet tall Crafted with huggable and durable materials, this gentle giant is ideal for playing and posing, perfect as a decorative piece in a nursery or anywhere in the home Soft polyester fabric is surface washable and encourages hugs and snuggling A whimsical catalyst for sparking the imagination and promoting creative play, it's sure to be a beloved member of any child’s menagerie Makes a great gift for ages 3 to 103, for hands-on, screen-free play

3. DDI 1932245 Giant Plush Frog Case of 6

Hop after this adorable giant plush frog. Great gift for your favorite amphibian lover. Really soft green plush material with yellow belly, face, and feet. This friendly giant has plastic eyes on top of his head with a charming red bow tie, and embroidered butterfly on his belly. Each frog has a sewn tag with UPC code. Not recommended for children under the age of 3 years.Color: green and yellow Dimensions: 28" tall, 14" across his arms Material: 100% polyester material 1932245- SKU: DLR48234

Hop after this adorable giant plush frog. Great gift for your favorite amphibian lover. Really soft green plush material with yellow belly, face, and feet. This friendly giant has plastic eyes on top of his head with a charming red bow tie, and embroidered butterfly on his belly. Each frog has a sewn tag with UPC code. Not recommended for children under the age of 3 years.Color: green and yellow Dimensions: 28" tall, 14" across his arms Material: 100% polyester material 1932245- SKU: DLR48234

4. American Made Giant Stuffed Black Buffalo 44 Inch Big Plush Bison

Made with high quality materials and superb craftsmanship. Red satin neck-ribbon bow can be easily removed. Generously sized at 44 inches. Made in the USA with American fabrics.

This OVERSIZED STUFFED BLACK BUFFALO is BIG! BIG! BIG! IT MEASURES A WHOPPING 44 inches LONG and 36 inches TALL and 18 inches WIDE. (That's almost 4-FEET LONG and more than THREE FEET TALL)! and.. he's FAT, SOFT and CUDDLY too:-) SIZE. SOFTNESS. SQUEEZABILITY. REALISTIC FEATURES. This stuffed brown Buffalo HAS IT ALL! You HAVE to SEE this big, beautiful, premium plush black color Buffalo IN PERSON! This is truly an AWESOME, SUPER-HUGE, STUNNING and REAL-LOOKING stuffed Buffalo. It is stuffed with a mixture of squishy soft filling and very firm filling. It's face, horns and extremities are VERY SOFT; and it's torso is still soft to the touch, but is also somewhat slightly firmer and more supple and less "squishy". This makes it stand proud and tall, and is still pleasingly snuggly . You will absolutely LOVE it. The highly detailed head, face and body makes this plush Buffalo so amazingly LOVABLE! And it's life-like horns and facial features make it a true standout. Quality-made in the USA with premium fabric and craftsmanship and great ATTENTION TO DETAIL. Real QUALITY. This is the ultimate in soft, plush Buffalo luxury. Perfect for cuddling and loving! (Just don't EAT it:-) This is SURE to bring a giant SMILE to someone's face! And they sure will remember YOU for giving such a great and memorable gift! Measures: over 44-inches long... (THAT'S ALMOST 4 FEET LONG)! and over 36-inches tall... (THAT'S MORE THAN 3 FEET TALL)! This stuffed Buffalo conforms to all child safety standards. Kids and adults alike will LOVE this real-looking LIFE SIZE STUFFED BUFFALO.

5. Giant Microbes Plush - Tick (Ixodes Scapularis)

Giant Microbes Plush - Tick (Ixodes Scapularis) These Giant Microbes Dolls are a Million times their Actual Size!GIANT microbes are health and science products for humorous, educational, collectible, and Smart fun!Products include printed cards with fun fascinating facts.Unique gifts for students, scientists, teachers, health professionals & anyone with a healthy sense of humor! All About Tick (Ixodes Scapularis) If you frequent wooded areas it's only a matter of time until you're bitten. Tick, tock, tick, tock... A super reminder to check for ticks when outdoors and a great gift for nature lovers! FACTS:In most of the world’s dark woods and grassy plains, tiny ticks are questing in search of blood. These little vampires can be as small as pinpoints or as large as grapes – but they have an uncanny ability to sense heat and carbon dioxide, and to identify the well-travelled paths that their victims are likely to traverse. When they sense the motion of a nearby host, they drop from the tips of grasses or leaves and plunge their barbed, fang-like hypostome into their victim’s neck (or any other convenient spot) and lap up to hundreds of times their body-weight until they are sated. Or removed. A kind of arthropod, ticks are not insects but arachnids related to scorpions and spiders. Hard ticks (such as deer ticks and dog ticks) have a plate-like scutum protecting their backs which gives them the comfort to feed for hours or days. Because diseases such as tularemia, Lyme disease, and Rocky- Mountain Spotted Fever tend not to be transmitted until dessert, there is often time to remove discovered ticks before lasting harm has been done. (Soft ticks, on the other hand, eat and run, dropping off after barely an hour.) To remove a tick, folk remedies involving heated pins, matches, or gasoline are best avoided – they can provoke the tick into regurgitating part of its meal, and infection along with it. Instead, the tick should be grasped with a tweezers as close to the skin as possible, flipped onto its back (slowly, so as not to dislodge the “head”, or mouthparts, in the skin), and then gently pulled until it is removed. But resist the temptation to drive a stake through its heart as that can help spread disease as well. A bath of alcohol should allow you to discard a tick safely – perhaps with a clove of garlic.

TICK

6. GIANTmicrobes Plush - Box of Blood cells

GIANTmicrobes Plush - Box of Blood cells These Giant Microbes Dolls are a Million times their Actual Size!GIANT microbes are health and science products for humorous, educational, collectible, and Smart fun!Products include printed cards with fun fascinating facts.Unique gifts for students, scientists, teachers, health professionals & anyone with a healthy sense of humor!All About the Box of Blood cells You won’t faint at the sight of these adorable Blood Cells. Replace your hemophobia and learn to love your plasma, platelets, and all the wonderful cells pulsing through your veins. After all, red blood cells dominate the 70 trillion cells and friendly bacteria in your body. You have about 20 trillion RBCs keeping you happy and energized! Blood Cellsthemed gift box includes these mini microbes: Red Blood Cell, White Blood Cell, Plasma, Platelet, and Antibody. Great educational learning tool and get well gift for sick person or science enthusiast. Clip them onto your backpack, keys, or anywhere! Includes key chain clips. All About Box of Blood Cells Red Blood Cell Red blood cells, or erythrocytes, contain the hemoglobin that carries oxygen and carbon dioxide around the body. (Erythro means red in Greek, and cyte translates to cell.) Hemoglobin gives red blood cells their Characteristic color. When it is oxygen-rich, it appears reddish; when oxygen-poor, it is darker and bluish. Although erythrocytes are flexible (which permits them to squeeze through capillaries), they typically have a distinctive biconcave shape that helps maximize surface area to facilitate the exchange of gases. White Blood Cell White blood cells, or Leukocytes, are your body’s white knights. If an enemy germ invades you, they ride to the rescue and fight to the death. There are several different kinds of leukocytes, and each has special skills to help protect you. Neutrophils race to the scene when bacteria attack. B cells neutralize viruses and T cells move in for the coup de grâce. Plasma Plasma is the pale liquid that makes up about 55% of your blood. The other blood components are suspended in plasma, and it allows them to travel through the blood vessels and around your body! Plasma itself plays a critical role in carrying waste products to the kidneys, liver, and lungs where they can be removed from the body. Plasma also helps maintain normal blood pressure and helps regulate the body’s temperature. Platelet Platelets, or thrombocytes, are the smallest cells (or cell fragments) in the blood.

Giant Microbes Plush Giant Microbes Blood Cells Set, NL240, Ed Supplies & Early Childhood, Health & NutritionEd Supplies & Early Childhood, Science, Health and NutritionTherapy and Rehab, Sensory Stimulation, TactileParty and Novelty, Plush Toys,SSW-NL240,SSW,NL240

7. Giant Microbes Plush - Mosquito - Culex-Pipiens

Giant Microbes Plush -Mosquito - Culex-Pipiens These Giant Microbes Dolls are a Million times their Actual Size!GIANT microbes are health and science products for humorous, educational, collectible, and Smart fun!Products include printed cards with fun fascinating facts.Unique gifts for students, scientists, teachers, health professionals & anyone with a healthy sense of humor! All About Aedes Mosquito - Culex-Pipiens Our mosquito's itching to come over and play. She can be there by dusk. There are about 3,000 species of mosquito, but culex pipiens is the most common. It is found almost all over the world, except in Antarctica. Spanish for "little fly," mosquitoes beat their wings between 300 and 600 times per second. The unnerving sound they create differs from species to species, and listening for the right note helps male and female mosquitoes coordinate their social lives to find suitable mates! But only female mosquitoes bite. Their eggs need the protein in blood to help develop. While culex pipiens females will happily snack on human blood, they tend to feed on birds – which implicates them in the transmission of the West Nile virus. The actual sting of a mosquito is rarely painful, and it is seldom even detected. However, the saliva injected to stop blood from clotting provokes the aggravating skin inflammation and itching associated with a bite. Calamine lotions, and other creams, can help soothe the pain. Of course, wearing longs pants and shirts, particularly at dawn and dusk, can help avoid bites in the first place. Mosquitoes are extremely attracted to the carbon dioxide you exhale, and they can detect it up to 75 feet away – so you can also try holding your breath! Better yet, try repellents, particularly ones that contain diethyltoluamide (DEET), picaridin, or lemon eucalyptus. She might just take the hint.

MOSQUITO

8. Giant Microbes Plush - Chlamydia (Chlamydia Trachomatis)

Giant Microbes Plush -Chlamydia (Chlamydia Trachomatis) Playing doctor is a game you don't want to lose. Know the rules. Our STDs are the perfect reminder to get tested and be safe. All AboutChlamydia (Chlamydia Trachomatis) FACTS: Chlamydia is perhaps the most common of all sexually transmitted diseases, though it is comparatively unsung. While it can produce symptoms such as discharges, burning sensations, abnormal bleeding, pain, and nausea, these symptoms are easily confused with those caused by gonorrhea. In addition, in nearly three quarters of women and nearly half of men chlamydia produces no symptoms at all. Untreated, the infection quietly spreads until it can attack fallopian tubes and ovaries, causing permanent damage to the female reproduction system, and in some cases even infertility. (It can also lead to epididymitis in men, which can cause sterility.) Fortunately, affordable and reliable testing is available for chlamydia – and it is highly responsive to antibiotics. Unfortunately, treatment is often tragically delayed until it is too late. In addition to its venereal impact, Chlamydia trachomatis is also responsible for trachoma, the leading cause of preventable blindness worldwide. Repeat infections with the bacteria eventually cause the eyelids to invert, and untreated scarring ultimately destroys the vision. Trachoma is primarily confined to the developing world where medical care is limited. However, because C. trachomatis bacteria can be transmitted from a mother to a child during birth, half of the children born to mothers with chlamydia enter the world with an eye infection – or worse: chlamydia has also been implicated in causing infant pneumonia, as well as premature- and still-births.

CHLAMYDIA

9. Giant Microbes Plush - Pneumonia (Streptococcus Pneumonia)

Giant Microbes Plush -Pneumonia (Streptococcus Pneumonia) These Giant Microbes Dolls are a Million times their Actual Size!GIANT microbes are health and science products for humorous, educational, collectible, and Smart fun!Products include printed cards with fun fascinating facts.Unique gifts for students, scientists, teachers, health professionals & anyone with a healthy sense of humor! All AboutPneumonia (Streptococcus Pneumonia) Pneumonia can take your breath away. FACTS:Pneumonia is a lung infection in which the small, air-exchanging sacs of the lungs (called alveoli) become inflamed and filled with fluid. It can come on suddenly and in serious cases, it can take your breath away. There are a number of causes of pneumonia, ranging from viruses to fungi to parasites to physical injury – through being caught in the rain without your coat is not among them. However, the most common cause of bacterial pneumonia infection is Streptococcus pneumoniae. As the ringleader of a gang of more than 80 Pneumococcus bacteria, Streptococcus pneumonia is such a common cause of pneumonia that a pneumonia vaccine has been developed to keep it (and 23 other of the worst kinds of Pneumococcus bacteria) at bay. The vaccine is recommended for those most susceptible to pneumonia infection, such as the elderly and those with respiratory diseases, weakened immune systems, or chronic illnesses. In addition, because pneumonia often occurs as a complication of influenza infection (or the flu), flu shots are also recommended for those at risk for pneumonia. However, unlike flu shots, one dose of the pneumonia vaccine provides long-term protection against the disease, though a follow-up dose is recommended in certain cases. If you’re at risk for pneumonia, don’t hold your breath. Take precautions, and breathe a sigh of relief.

Knick Knack Toy Shack Giant Microbes Plush - Pneumonia (Streptococcus Pneumonia), Multicolor These Giant Microbes Dolls are a Million times their Actual Size Products include printed cards with fun fascinating facts. GIANT microbes are health and science products for humorous, educational, collectible, and Smart fun! Unique gifts for students, scientists, teachers, health professionals & anyone with a healthy sense of humor!

10. Giant Microbes Plush - Kissing Disease (Mono)

Giant Microbes Plush - Kissing Disease (Mono) These Giant Microbes Dolls are a Million times their Actual Size!GIANT microbes are health and science products for humorous, educational, collectible and Smart fun!Products include printed cards with fun fascinating facts.Unique gifts for students, scientists, teachers, health professionals & anyone with a healthy sense of humor! All AboutKissing Disease (Mono) FACTS: The Kissing Disease, or mononucleosis, is caused by the Epstein-Barr virus (named after it discovers Michael Epstein and Y. M. Barr.) More than 95% of the population is infected! Most people catch the virus at a very young age, at which time the symptoms are often too mild to be noticed. However, those who catch it when they are young adults (or older) suffer from sore throats, swollen lymph glands, and extreme malaise. In addition, the spleen can become enlarged – sports and strenuous activities must be avoided to prevent rupture. Epstein-Barr virus also causes an increase in the level of "mononuclear" white blood cells in the blood, which is how the disease got its nickname. Nevertheless, Epstein-Barr is not very contagious. Transmission requires close contact such as kissing or sharing drinks. And with an incubation period of 4-7 weeks, it can be a while before you know whether you’ve caught it. Most people get over Epstein-Barr in a couple of weeks – though it can take up to a year to kiss the virus goodbye!

Giant Microbes Plush - Kissing Disease (Mono)