The Best Alka-Seltzer 2025

Updated On December 30th, 2025

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Rank Product Name Score
1
Alka-Seltzer Heartburn Relief Tablets- Lemon Lime, 36 Count Boxes

Alka-Seltzer Heartburn Relief Tablets- Lemon Lime, 36 Count Boxes

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96%
2
Alka-Seltzer Extra Strength Heartburn Relief Chews Assorted Fruit, 36 Count

Alka-Seltzer Extra Strength Heartburn Relief Chews Assorted Fruit, 36 Count

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94%
3
Alka-seltzer Extra Strength, 24-Count

Alka-seltzer Extra Strength, 24-Count

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88%
4
Alka- Seltzer Lemon Lime, 36 Count

Alka- Seltzer Lemon Lime, 36 Count

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88%
5
Alka-Seltzer Tablets, Original, 24 Ct

Alka-Seltzer Tablets, Original, 24 Ct

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86%
6
Alka-Seltzer Original Antacid & Pain Relief, 36 ct

Alka-Seltzer Original Antacid & Pain Relief, 36 ct

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86%
7
Alka-Seltzer Single Dose Packets, 36 / Box

Alka-Seltzer Single Dose Packets, 36 / Box

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0%
8
Alka Seltzer: Pain Reliever/Alertness Aid Citrus Flavor Wake-Up Call, 16 ct

Alka Seltzer: Pain Reliever/Alertness Aid Citrus Flavor Wake-Up Call, 16 ct

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0%
9
Alka-seltzer As Pl Cold Liquid-gel 20s 4dz W/peh

Alka-seltzer As Pl Cold Liquid-gel 20s 4dz W/peh

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0%
10
Alka-seltzer Asp Allergy 24ct Tabs

Alka-seltzer Asp Allergy 24ct Tabs

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0%

1. Alka-Seltzer Heartburn Relief Tablets- Lemon Lime, 36 Count Boxes

Alka-Seltzer Heartburn Relief Tablets- Lemon Lime, 36 Count Boxes
96%

Our Score

Fast, Cooling Relief of: Heartburn and Acid Indigestion Anhydrous Citric Acid / Antacid Sodium Bicarbonate / Antacid Alka-Seltzer? Heartburn Relief extinguishes the fire of your worst heartburn. Its aspirin-free effervescent formula starts to work the instant you take it. For the relief of: Heartburn Acid Indigestion Upset stomach associated with these symptoms Directions Fully dissolve 2 tablets in 4 oz of water before taking. Adults and children 12 years and over 2 tablets every 4 hours as needed, or as directed by a doctor. Do not exceed 8 tablets in 24 hours Adults 60 years and over: 2 tablets every 4 hours as needed, or as directed by a doctor. Do not exceed 4 tablets in 24 hours Children under 12 years Consult a doctor Free Of Aspirin Disclaimer These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

Alka-Seltzer Heartburn Relief Tablets- Lemon Lime, 36 Count Boxes

2. Alka-Seltzer Extra Strength Heartburn Relief Chews Assorted Fruit, 36 Count

Alka-Seltzer Extra Strength Heartburn Relief Chews Assorted Fruit, 36 Count
94%

Our Score

Fast, fruit-flavored heartburn relief with no chalky taste. This is your go-to on the go-go kind of fast relief of heartburn, indigestion and upset stomach. Relief Chews are easy to take with you and come in great-tasting (not chalky or gritty) assorted fruit flavor.

Alka-Seltzer Extra Strength Heartburn Relief Chews Assorted Fruit, 36 Count: EASY TO TAKE FORM: Alka-Seltzer offers easy to eat and delicious chewable tablets. MULTI-SYMPTOM RELIEF: fast relief of heartburn, acid indigestion, sour stomach, and upset stomach related to these symptoms. DELICIOUS FLAVORS: This product comes in delicious lemon, orange and strawberry flavors. FAST ACTING: starts neutralizing acid in seconds! TRUSTED BRAND: Alka-Seltzer has been a trusted brand for over 80 years.

3. Alka-seltzer Extra Strength, 24-Count

Alka-seltzer Extra Strength, 24-Count
88%

Our Score

The name you trust for fast and effective relief. Active Ingredients: Per Tablet: Aspirin 500 mg; Citric Acid 1000 mg; Sodium Bicarbonate (Heat-Treated) 1985 mg Inactive Ingredients: Flavor; Each Tablet Contains: Sodium 588 mg Uses: For the relief of: heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains; upset stomach with headache from over-indulgence in food and drink; headache, body aches, and pain alone. Alka-Seltzer Extra Strength in water contains principally the antacid sodium citrate and the analgesic sodium acetylsalicylate.

Alka-seltzer Extra Strength, 24 Count

4. Alka- Seltzer Lemon Lime, 36 Count

Alka- Seltzer Lemon Lime, 36 Count
88%

Our Score

The name you trust for fast and effective relief. Active Ingredients: Per Tablet: Aspirin 325 mg; Citric Acid 1000 mg; Sodium Bicarbonate (Heat-Treated) 1700 mg Inactive Ingredients: Aspartame; Calcium Silicate; Dimethylpolysiloxane; Docusate Sodium; Flavor; Povidone; Sodium Benzoate; Each Tablet Contains: Sodium 503 mg Uses: For the relief of: heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains; upset stomach with headache from overindulgence in food or drink; pain alone (headache or body ache and muscular aches and pains). Alka-Seltzer Lemon-Lime in water contains principally the antacid sodium citrate and the analgesic sodium acetylsalicylate.

Alka- Seltzer Lemon Lime, 36 Count

5. Alka-Seltzer Tablets, Original, 24 Ct

Alka-Seltzer Tablets, Original, 24 Ct
86%

Our Score

? Place two (2) tablets in 4 oz. of water. Dissolve tablets completely. ? You do not have to drink any of the residue that may be on the bottom of the glass. The medicines of Alka-Seltzer? are in the water.

Alka-Seltzer Tablets, Original, 24 Ct

6. Alka-Seltzer Original Antacid & Pain Relief, 36 ct

Alka-Seltzer Original Antacid & Pain Relief, 36 ct
86%

Our Score

Alka-Seltzer Original Effervescent Antacid Tablets 36 Ea Take Alka-Seltzer any time - morning, noon, or night - when you need relief from acid indigestion, upset stomach, or heartburn with headache or body aches and pains Alka-Seltzer

Alka-Seltzer Original Effervescent Tablets with Aspirin, 36-count Boxes

7. Alka-Seltzer Single Dose Packets, 36 / Box

Alka-Seltzer Single Dose Packets, 36 / Box
0%

Our Score

Alka-Seltzer delivers quick relief when you need it most. Effervescent tablets dissolve fast and are ready to work the instant you take them. Alka-Seltzer treats indigestion, upset stomach, and heartburn with headaches. Each packet contains two tablets.

Delivers quick relief when you need it most Effervescent tablets dissolve fast and are ready to work the instant you take them Treats indigestion, upset stomach, and heartburn with headaches Each packet contains 2 tablets 36 / Box

8. Alka Seltzer: Pain Reliever/Alertness Aid Citrus Flavor Wake-Up Call, 16 ct

Alka Seltzer: Pain Reliever/Alertness Aid Citrus Flavor Wake-Up Call, 16 ct
0%

Our Score

Alka Seltzer: Pain Reliever/Alertness Aid Citrus Flavor Wake-Up Call, 16 ct

Alka Seltzer: Pain Reliever/Alertness Aid Citrus Flavor Wake-Up Call, 16 ct

9. Alka-seltzer As Pl Cold Liquid-gel 20s 4dz W/peh

Alka-seltzer As Pl Cold Liquid-gel 20s 4dz W/peh
0%

Our Score

short description is not available

Alka-seltzer As Pl Cold Liquid-gel 20s 4dz W/peh

10. Alka-seltzer Asp Allergy 24ct Tabs

Alka-seltzer Asp Allergy 24ct Tabs
0%

Our Score

short description is not available

Alka-seltzer Asp Allergy 24ct Tabs