The Best Insect Bite Treatment 2025

Updated On May 18th, 2025

Looking for the best Insect Bite Treatment? You aren't short of choices in 2022. The difficult bit is deciding the best Insect Bite Treatment for you, but luckily that's where we can help. Based on testing out in the field with reviews, sells etc, we've created this ranked list of the finest Insect Bite Treatment.

Rank Product Name Score
1
Gold Bond Rapid Relief Anti Itch Cream, 2 oz

Gold Bond Rapid Relief Anti Itch Cream, 2 oz

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100%
2
Cortizone 10 Anti-Itch Crème with Aloe 1oz

Cortizone 10 Anti-Itch Crème with Aloe 1oz

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94%
3
Cortizone-10 Max Strength Cream, 2 oz

Cortizone-10 Max Strength Cream, 2 oz

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94%
4
Cortizone 10 Plus Ultra Moisturizing Anti Itch Cream with 1% Hydrocortisone, 1 oz.

Cortizone 10 Plus Ultra Moisturizing Anti Itch Cream with 1% Hydrocortisone, 1 oz.

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94%
5
Aveeno Maximum Strength 1% Hydrocortisone Anti-Itch Cream, Triple Oat

Aveeno Maximum Strength 1% Hydrocortisone Anti-Itch Cream, Triple Oat

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94%
6
Cortizone 10 Maximum Strength Anti Itch Ointment with Hydrocortisone, 1 oz.

Cortizone 10 Maximum Strength Anti Itch Ointment with Hydrocortisone, 1 oz.

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92%
7
Cortizone 10 Maximum Strength Anti Itch Ointment (2 Oz)

Cortizone 10 Maximum Strength Anti Itch Ointment (2 Oz)

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92%
8
Benadryl Extra Strength Anti-Itch Cooling Spray, Travel Size, 2 fl. oz

Benadryl Extra Strength Anti-Itch Cooling Spray, Travel Size, 2 fl. oz

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92%
9
Therapik 2pk Mosquito Bite Relievers

Therapik 2pk Mosquito Bite Relievers

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86%
10
Tender After Bite The Itch Eraser, 0.5 oz

Tender After Bite The Itch Eraser, 0.5 oz

Check Price
84%

1. Gold Bond Rapid Relief Anti Itch Cream, 2 oz

Gold Bond Rapid Relief Anti Itch Cream, 2 oz
100%

Our Score

Gold Bond Rapid Relief Anti-Itch Cream delivers Fast Acting Cooling Relief for Itch and also relieves minor pain. Steroid Free and Hydrocortisone Free, this Maximum Strength formula delivers twice the itch fighting medicines of any Hydorcortisone formula. You can feel it working even as you apply it. It contains colling aloe and Vitamin E to help relief pain and itching assocaited with minor skin irritations, minor cuts, minor burns, minor sunburns, scrapes, insect bites, and rashes due to poison ivy, poison oak, or poison sumac.

The quick fix for almost every itch Medicated healing since 1908 2-oz value size Delivers 2 itch relieving ingredients plus aloe and vitamin E to soothe and calm your skin fast Contains no steroids or hydrocortisones Provides relief from minor skin irritations, cuts, burns, sunburns, rashes due to poison ivy, poison oak or poison sumac, scrapes and insect bites Package contains 2 oz of anti-itch healing cream

2. Cortizone 10 Anti-Itch Crème with Aloe 1oz

Cortizone 10 Anti-Itch Crème with Aloe 1oz
94%

Our Score

There are many causes of itching, including those that may occur all over the whole body or only in a specific location. Cortizone 10 Anti-Itch Creme with Aloe is made with the #1 itch medicine recommended by doctors* and is great at relieving the common causes of itching including: skin irritation & rashes, inflammation & redness, insect bites, & poison ivy. The non-greasy Creme is designed to go on smoothly and penetrate quickly to relieve itch fast using the strongest itch medicine without a prescription, hydrocortisone 1%. It also contains healing aloe to soothe itchy, irritated skin. Cortizone 10 provides fast itch relief that lasts 10 hours! Cortizone 10 Anti-Itch Creme with Aloe is available in 0.5oz, 1 oz, and 2oz. *Refers to the ingredient hydrocortisone

Cortizone 10 Anti-Itch Crème with Aloe 1oz Strongest Itch Medicine without a Prescription Contains 1% hydrocortisone Contains soothing aloe Non-Greasy and Goes On Smoothly

3. Cortizone-10 Max Strength Cream, 2 oz

Cortizone-10 Max Strength Cream, 2 oz
94%

Our Score

Eliminate tingling and irritation of the skin using Cortizone 10 Maximum Strength 1% Hydrocortisone Anti-Itch. This serious medicine absorbs quickly into the skin restoring a natural balance to stop the itch and help prevent infections. This anti-itch cream with healing aloe soothes, cools and calms. It immediately begins to constrict the blood vessels resulting in reduced swelling and redness on the skin. This Cortizone 10 Maximum Strength 1% Hydrocortisone Anti-Itch creme gives you fast, temporary relief of skin irritations, inflammation, redness, insect bites and poison ivy, poison oak and sumac. It's available in a convenient 2.0-oz size.

Cortizone 10 Maximum Strength 1% Hydrocortisone Anti-Itch Creme, 2 oz: Cortizone anti-itch creme, 1% hydrocortisone, maximum strength Misc: 2-oz value Relieves itch fast Strongest itch medicine without a prescription (refers to the ingredient hydrocortisone) Skin irritation and rashes, inflammation and redness, insect bites, poison ivy Absorbs quickly Cortizone anti-itch medicine with healing aloe No. 1 itch medicine (refers to the ingredient hydrocortisone) doctors recommend Serious medicine, fast comfort Feel the heal www.Chattem.com For more information please visit www.Cortizone10.com Recommended for adults and children 2-years of age and older

4. Cortizone 10 Plus Ultra Moisturizing Anti Itch Cream with 1% Hydrocortisone, 1 oz.

Cortizone 10 Plus Ultra Moisturizing Anti Itch Cream with 1% Hydrocortisone, 1 oz.
94%

Our Score

Dry, itchy skin calls for soothing moisture. That's why there's Cortizone 10 Maximum Strength Plus Ultra Moisturizing Anti-Itch Creme. Made with maximum strength hydrocortisone*, the #1 itch medicine recommended by doctors, this anti-itch creme works fast to temporarily relieve itch. Maximum Strength Cortizone 10 Plus Ultra Moisturizing gets to work fast and provides itch relief for hours. This hydrating anti-itch creme also features 10 moisturizers, including aloe, to provide more than just itch relief. Use Cortizone 10 Plus Ultra Moisturizing Creme for itch associated with eczema, psoriasis, and dry, itchy skin. Stock up on Cortizone 10 Maximum Strength Plus Ultra Moisturizing Anti-Itch Creme so you always have hydrating itch relief on hand. *1% hydrocortisone is the maximum strength available without a prescription. DIRECTIONS: Adults and children 2 years of age and older: Apply to the affected area not more than 3 to 4 times daily. For children under 2 years of age: Ask a doctor.

Cortizone 10 Plus Ultra Moisturizing Anti Itch Cream (1 Oz) CONTAINS: One (1) 1-oz. tube of Cortizone 10 Maximum Strength Plus Ultra Moisturizing Anti-Itch Creme FAST & LONG LASTING: Cortizone 10 Ultra Moisturizing Anti-Itch Creme relieves itching fast and lasts for hours STOP THE ITCHSANITY: This maximum strength anti-itch creme contains maximum strength hydrocortisone, the #1 itch medicine recommended by doctors 10 NOURISHING INGREDIENTS: Cortizone 10 Plus Ultra Moisturizing contains 10 moisturizers, including aloe, and vitamins A and E to help make skin feel softer RELIEVES ITCH: Maximum Strength Cortizone 10 helps relieve itch associated with minor skin irritations and rashes due to insect bites, psoriasis, poison ivy and more

5. Aveeno Maximum Strength 1% Hydrocortisone Anti-Itch Cream, Triple Oat

Aveeno Maximum Strength 1% Hydrocortisone Anti-Itch Cream, Triple Oat
94%

Our Score

Maximum Strength Aveeno 1% Hydrocortisone Anti-Itch Cream with a fragrance-free, dye-free, non-comedogenic formula designed for longer-lasting itch relief. Enriched with Triple Oat, Aloe and Vitamin E, this skin-soothing cream provides temporary relief from the itching associated with minor skin irritations and rashes due to eczema, psoriasis, insect bites, poison ivy/oak/sumac, soaps, detergents, cosmetics, or jewelry. From the dermatologist-recommended skincare brand for over 70 years, Aveeno uses the goodness of nature and the power of science to keep your skin looking healthy and feeling balanced.

Max-strength Aveeno 1% Hydrocortisone Anti-Itch Cream is formulated for longer-lasting itch relief Maximum-strength cream is specially formulated for longer-lasting, effective itch relief Hydrocortisone cream with Triple Oat to effectively relieve itch & soothe skin irritations Enriched with Aloe & Vitamin E, this fragrance-free itch relief cream helps calm dry, itchy skin Suitable for use on skin affected by eczema, psoriasis, or insect bites Relieves minor irritations due to poison ivy/oak/sumac, soaps, detergents, cosmetics, or jewelry Soothing anti-itch cream from the dermatologist-recommended skincare brand for over 70 years Aveeno uses the goodness of nature & the power of science to keep skin healthy looking

6. Cortizone 10 Maximum Strength Anti Itch Ointment with Hydrocortisone, 1 oz.

Cortizone 10 Maximum Strength Anti Itch Ointment with Hydrocortisone, 1 oz.
92%

Our Score

Water-resistant itch relief formula that works fast and lasts for hours. Try Cortizone 10 Maximum Strength Ointment. This anti-itch ointment is formulated with maximum strength hydrocortisone*, the #1 itch medicine recommended by doctors, to help stop itching fast and provide relief for hours. This Cortizone 10 Ointment formula is designed to be water-resistant, with a petrolatum base, which forms an occlusive barrier to help keep the affected area clean and lock in moisture. Use Maximum Strength Cortizone 10 Ointment to help temporarily relieve itch associated with minor skin irritation and rashes due to insect bites; psoriasis; and poison ivy, oak, and sumac. Stock up on 1-ounce tubes of Cortizone 10 Maximum Strength Ointment so you always have itch relief on hand. 1% hydrocortisone is the maximum strength available without a prescription.

CONTAINS: One (1) 1-oz. tube of Cortizone 10 Maximum Strength Ointment FAST RELIEF: Cortizone 10 Anti-Itch Ointment relieves itching fast and lasts for hours STOP THE ITCHSANITY: Cortizone 10 Ointment contains maximum strength hydrocortisone, the #1 itch medicine recommended by doctors\ RELIEVES ITCH: Maximum Strength Cortizone 10 helps relieve itch associated with minor skin irritations and rashes due to insect bites, psoriasis, poison ivy and more WATER-RESISTANT FORMULA: This anti-itch ointment locks in moisture and helps keep the affected area clean while hydrocortisone relieves the itch

7. Cortizone 10 Maximum Strength Anti Itch Ointment (2 Oz)

Cortizone 10 Maximum Strength Anti Itch Ointment (2 Oz)
92%

Our Score

Got itchy skin? Try Cortizone 10 Maximum Strength Ointment. This anti-itch ointment is formulated with maximum strength hydrocortisone*, the #1 itch medicine recommended by doctors, to help stop itching fast and provide relief for hours. This Cortizone 10 Ointment formula is designed to be water-resistant, with a petrolatum base, which forms an occlusive barrier to help keep the affected area clean and lock in moisture. Use Maximum Strength Cortizone 10 Ointment to help temporarily relieve itch associated with minor skin irritations and rashes associated with insect bites; psoriasis; and poison ivy, oak, and sumac. Stock up on 2-ounce tubes of Cortizone 10 Maximum Strength Ointment so you always have itch relief on hand. *1% hydrocortisone is the maximum strength available without a prescription. DIRECTIONS: Adults and children 2 years of age and older: Apply to the affected area not more than 3 to 4 times daily. For children under 2 years of age: Ask a doctor.

CONTAINS: One (1) 2-oz. tube of Cortizone 10 Maximum Strength Ointment FAST RELIEF: Cortizone 10 Anti-Itch Ointment relieves itching fast and lasts for hours STOP THE ITCHSANITY: Cortizone 10 Ointment contains maximum strength hydrocortisone, the #1 itch medicine recommended by doctors RELIEVES ITCH: Maximum Strength Cortizone 10 helps relieve itch associated with minor skin irritations and rashes due to insect bites, psoriasis, poison ivy and more WATER-RESISTANT FORMULA: This anti-itch ointment locks in moisture and helps keep the affected area clean while hydrocortisone relieves the itch

8. Benadryl Extra Strength Anti-Itch Cooling Spray, Travel Size, 2 fl. oz

Benadryl Extra Strength Anti-Itch Cooling Spray, Travel Size, 2 fl. oz
92%

Our Score

Benadryl Extra Strength Anti-Itch Cooling Spray provides fast relief from skin irritation and itching. Made with 2% diphenhydramine HCI topical analgesic and 0.1% zinc acetate skin protectant, this itch relief spray begins to work on contact to relieve the pain and itching associated with most outdoor itches including insect bites, sunburn, scrapes, and minor skin irritations, burns, and cuts. It also dries rashes caused by poison ivy, poison oak, and poison sumac. Benadryl Extra Strength Itch Cooling Spray works when you need it most and is intended for ages two and up.

Extra Strength Anti-Itch Cooling Spray provides fast, cooling relief for most outdoor itches Itch relief spray begins to work on contact to provide fast relief from skin pain and itching Relieves itching associated with insect bites, sunburn, scrapes, minor skin irritations & burns Topical Analgesic soothes rashes caused by poison ivy, poison oak, and poison sumac The bug bite itch relief spray can be applied directly to insect and mosquito bites Itch relief spray contains 2% diphenhydramine HCI topical analgesic Cooling spray formula contains 0.1% zinc acetate skin protectant Extra-strength anti-itch topical analgesic/skin protectant is intended for use by those ages 2+

9. Therapik 2pk Mosquito Bite Relievers

Therapik 2pk Mosquito Bite Relievers
86%

Our Score

Therapik 2pk Mosquito Bite Relievers

Therapik 2pk Mosquito Bite Relievers

10. Tender After Bite The Itch Eraser, 0.5 oz

Tender After Bite The Itch Eraser, 0.5 oz
84%

Our Score

The Itch Eraser, Original .5 fl oz (14 ml) Trusted formula. Pharmacist preferred for instant relief! Be ready for mosquitoes; black flies; fleas; ticks; chiggers; horse flies and other bites. Be ready for summer! AfterBite Original is the trusted itch eraser formula for the whole family. For mosquitoes, black flies, ticks and more, there's nothing like it in your medicine cabinet. Keep AfterBite at home, in your car, in your tackle box and camper. Don't let insect bites ruin your family fun. Satisfaction guaranteed. . Temporarily protects and helps relieve minor skin irritation and itching due to: insect bites and stings; poison ivy, oak or sumac. Dab directly on bite or sting and rub gently. If itching persists re-apply as necessary. For a bee sting, remove stinger before treatment. Adults and children 2 years and older apply to affected area - children under 2 years consult a doctor. For external use only. When using this product do not get in eyes. Stop use and ask a doctor if: condition worsens; symptoms last more than 7 days or clear up and occur again within a few days. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. If in eyes flush with water for 15 minutes and call a doctor. .5 fl oz (14 ml) Littleton, NH 03561

The Itch Eraser, Original Trusted formula. Pharmacist preferred for instant relief! Be ready for mosquitoes; black flies; fleas; ticks; chiggers; horse flies and other bites. Be ready for summer! AfterBite Original is the trusted itch eraser formula for the whole family. For mosquitoes, black flies, ticks and more, there's nothing like it in your medicine cabinet. Keep AfterBite at home, in your car, in your tackle box and camper. Don't let insect bites ruin your family fun. Satisfaction guaranteed.


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