The Best Mattress Covers & Protectors 2025

1. Merchandise

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Merchandise

2. Allergy Relief Standard Pillow Cover and Twin Mattress Cover set

Allergy Relief Pillow and Mattress Protectors keep allergens away and provide a waterproof dust mite barrier for your entire bed.

Allergy Relief Pillow and Mattress Protectors keep allergens away. Provide a dust mite barrier for your entire bed Waterproof Comfortable fabric feel

3. Merchandise

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Merchandise Merchandise Great for adults

4. Merchandise

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Merchandise

5. Cool Nights King Pillow Covers, Set of 2

Cool Nights Pillow Covers are clinically proven to minimize the impact of hot flashes and night sweats.

Cool Sensations Pillow Protectors surround you with cool, dry comfort trhoughout the night. Clinically proven to: Increase the amount of uninterupted sleep Improves sleep quality by over 60% Reduce the effects of sweating

6. Saddle-Style Waterproof Mattress Protector

End late night bedding changes with this mattress protector. This saddle-styled protector wraps around the mattress over your fitted sheet to stay in place and protect your child's bedding from late night accidents. Perfect for use during potty training.

Pad measures 34" x 36" Tuck tails wrap under mattress and over bedding For use with a twin size bed 100% waterproof Holds up to 6 cups of liquid Fabric: cotton, polyester and rayon Care: machine wash and dry

7. AllerEase Allergy Waterproof Durable Mattress Protector, Twin Size, for Adults

The AllerEase Allergy Waterproof Durable Mattress Protector is designed for adults to provide a reliable defense against dust mites, allergens, and other microscopic particles. This durable protector fully encases mattresses up to 12.0 inches deep with a secure zippered closure, creating a complete barrier that helps promote a healthier sleeping environment. Measuring 75.0 inches in length, this protector is perfect for Twin-sized beds. Its waterproof construction adds an extra layer of protection against spills and stains, ensuring your mattress stays clean and fresh for longer.

Durable Fabric Blend: Top fabric is 55% cotton and 45% polyester laminated to polyethylene. Zippered Full Enclosure: Protects adults by keeping allergens away from sleepers. Waterproof Barrier: Provides effective protection against spills and stains. Fits Various Sizes: Available in Twin, Full, Queen, King, and Cal King options. Deep Mattress Fit: Designed for mattresses up to 12 inches deep. Easy to Maintain: Simply machine wash in hot water and tumble dry on low heat.

8. Allergy Waterproof Durable Mattress Protector

Protect yourself from dust mites and allergens with the Allergy Durable Mattress Protector. It zips around your mattress to create an effective barrier to microscopic particles, including dust, dust mites and other allergens.

Allergy Durable Mattress Protector: Top fabric is 55% cotton/45% polyester laminated to a durable polyethylene film Back and side fabric is 100% polypropylene Zippered construction encases the entire mattress to keep allergens away from the sleeper Waterproof Easy-care product; simply wash in hot water and tumble dry at low heat Fits mattresses up to 12 inches deep Available in Twin, Full, Queen, King and Cal King

9. Allergy Waterproof Durable Mattress Protector

Protect yourself from dust mites and allergens with the Allergy Durable Mattress Protector. It zips around your mattress to create an effective barrier to microscopic particles, including dust, dust mites and other allergens.

Allergy Durable Mattress Protector: Top fabric is 55% cotton/45% polyester laminated to a durable polyethylene film Back and side fabric is 100% polypropylene Zippered construction encases the entire mattress to keep allergens away from the sleeper Waterproof Easy-care product; simply wash in hot water and tumble dry at low heat Fits mattresses up to 12 inches deep Available in Twin, Full, Queen, King and Cal King

10. Allergy Waterproof Durable Mattress Protector

This mattress protector thoroughly encases your mattress to provide an effective barrier against allergens

Allergy Durable Mattress Protector: Top fabric is 55% cotton/45% polyester laminated to a durable polyethylene film Back and side fabric is 100% polypropylene Zippered construction encases the entire mattress to keep allergens away from the sleeper Waterproof Easy-care product; simply wash in hot water and tumble dry at low heat Fits mattresses up to 12 inches deep Available in Twin, Full, Queen, King and Cal King