Do changes in the cerebrovascular system precede or follow clinical onset of Alzheimer's Disease? In this book a distinguished group of contributors addressES this question and explores the extent to which the pathological changes found in the brains of persons with Alzheimer's disease are related to cerebral blood flow, perfusion, and blood-brain barrier dysfunction. Other topics include the role of stroke, heart disease, diabetes, menopause, and blood pressure on the evolution of Alzheimer's disease; genetic factors affecting the cerebrovasculature; brain metabolic and chronic cerebral hypoperfusion; and the influence of the cerebromicrovasculature on neuronal function--all issues of critical importance in orienting research lines that may provide new answers to the Alzheimer puzzle.

Cerebrovascular Pathology in Alzheimer's Disease, Used [Paperback]