A thriller that centers on Isabella El-Ibrahimi, the American wife of Egyptian-born chemical engineer Anwar El-Ibrahimi, who disappears on a flight from South Africa to Washington. Isabella desperately tries to track her husband down, while a CIA analyst at a secret detention facility outside the U.S. is forced to question his assignment as he becomes party to the man's unorthodox interrogation.

Louis Feuillade, director of the Fantômas films, returns with this ten-episode espionage series following tenacious journalist Philippe Guerande (Édouard Mathé) as he works to infiltrate a notorious international crime ring known as The Vampires, and encounters sensuous burglar Irma Vep (Musidora) -- the elusive, black-clad beauty at the center of the enigmatic secret society.