The Best Clinical Strength Antiperspirants 2025

Updated On June 24th, 2025

Looking for the best Clinical Strength Antiperspirants? You aren't short of choices in 2022. The difficult bit is deciding the best Clinical Strength Antiperspirants for you, but luckily that's where we can help. Based on testing out in the field with reviews, sells etc, we've created this ranked list of the finest Clinical Strength Antiperspirants.

Rank Product Name Score
1
Secret Clinical Soft Solid Antiperspirant and Deodorant, Light & Fresh, 2.6 oz

Secret Clinical Soft Solid Antiperspirant and Deodorant, Light & Fresh, 2.6 oz

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94%
2
Secret Clinical Soft Solid Antiperspirant Deodorant for Women, Light & Fresh, 1.6 oz

Secret Clinical Soft Solid Antiperspirant Deodorant for Women, Light & Fresh, 1.6 oz

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92%
3
Degree Clinical Protection Antiperspirant Deodorant for Women Shower Clean, 1.7 oz

Degree Clinical Protection Antiperspirant Deodorant for Women Shower Clean, 1.7 oz

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92%
4
Secret Clinical Soft Solid Antiperspirant and Deodorant, Unscented Sensitive, 1.6 oz

Secret Clinical Soft Solid Antiperspirant and Deodorant, Unscented Sensitive, 1.6 oz

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90%
5
Certain Dri Clinical Strength Antiperspirant Roll-on 1.2 Oz

Certain Dri Clinical Strength Antiperspirant Roll-on 1.2 Oz

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90%
6
Clinical Protection Sheer Powder Anti-Perspirant by Degree for Women - 1.7 oz Deodorant Stick

Clinical Protection Sheer Powder Anti-Perspirant by Degree for Women - 1.7 oz Deodorant Stick

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88%
7
Certain Dri Everyday Strength Clinical Antiperspirant + Deodorant, Solid, 2.6 oz

Certain Dri Everyday Strength Clinical Antiperspirant + Deodorant, Solid, 2.6 oz

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88%
8
Revlon Mitchum Clinical Performance Anti-Perspirant & Deodorant, 2.5 oz

Revlon Mitchum Clinical Performance Anti-Perspirant & Deodorant, 2.5 oz

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86%
9
Mitchum Smart Solid Clinical Performance Powder Anti-Perspirant & Deodorant for Women, 2.5 oz

Mitchum Smart Solid Clinical Performance Powder Anti-Perspirant & Deodorant for Women, 2.5 oz

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72%
10
Degree Clinical Protection Clean Anti-Perspirant & Deodorant Degree Men 1.7 oz

Degree Clinical Protection Clean Anti-Perspirant & Deodorant Degree Men 1.7 oz

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0%

1. Secret Clinical Soft Solid Antiperspirant and Deodorant, Light & Fresh, 2.6 oz

Secret Clinical Soft Solid Antiperspirant and Deodorant, Light & Fresh, 2.6 oz
94%

Our Score

Secret Clinical Strength Antiperspirant and Deodorant for Women is clinically proven protection for 3 types of sweat; 1) stress sweat, 2) heat sweat and 3) activity sweat. Secret Clinical Strength offers the wetness protection of a prescription-strength product formulated to be gentle on skin, making it perfect for everyday use. Secret Clinical Strength Soft Solid-advanced protection to take on even the most stressful days. Also available in invisible solid and clear gel.

Clinical Strength protection to fight 3 types of sweat - stress, heat, and activity Clinically Proven Prescription strength wetness protection 3X* Stress Sweat Protection (*vs. the wetness protection required of an ordinary antiperspirant) Designed with female dermatologists Certified Cruelty-Free by PETA 72 HR sweat protection pH balancing minerals #1 selling clinical antiperspirant brand

2. Secret Clinical Soft Solid Antiperspirant Deodorant for Women, Light & Fresh, 1.6 oz

Secret Clinical Soft Solid Antiperspirant Deodorant for Women, Light & Fresh, 1.6 oz
92%

Our Score

Secret Clinical Strength for Woman is the #1 Clinical Strength Antiperspirant. This antiperspirant keeps stress sweat in check with 4X the stress sweat protection* (*Vs. the protection required of an ordinary antiperspirant) 1 application, 0 reapplication, sweat protection for 48 hours Sweat Protection Designed For Your Body's Changes Secret Clinical Strength is the #1 selling clinical antiperspirant brand Enjoy that fresh-out-of-the-shower smell all day with Light & Fresh scent Secret Clinical Strength Soft Solid Antiperspirant and Deodorant, Light & Fresh scent

Clinical Strength protection to fight 3 types of sweat - stress, heat, and activity Clinically Proven Prescription strength wetness protection 3X* Stress Sweat Protection (*vs. the wetness protection required of an ordinary antiperspirant) Sweat Protection Designed For Your Body's Changes Certified Cruelty-Free by PETA 72 HR sweat protection pH balancing minerals Secret Clinical Strength Soft Solid Antiperspirant Deodorant for Women, Light & Fresh, 1.6 oz

3. Degree Clinical Protection Antiperspirant Deodorant for Women Shower Clean, 1.7 oz

Degree Clinical Protection Antiperspirant Deodorant for Women Shower Clean, 1.7 oz
92%

Our Score

Degree Clinical Protection Antiperspirant Deodorant for Women Shower Clean, 1.7 oz. Degree Clinical Protection Shower Clean Antiperspirant Deodorant delivers prescription-strength wetness protection, so you can face the day with confidence. This antiperspirant for women features 72-hour sweat and odor protection and the bright floral scent of rose and jasmine, blended with delicate fruit for an invigorating, clean feeling. Only Degree has Motion Sense technology that moves in sync with your body. This clinical strength antiperspirant deodorant releases a burst of subtle fragrance every time you move, for nonstop protection. Degree Clinical Protection Shower Clean Antiperspirant Deodorant keeps you feeling fresher, drier, and more confident. This powerful antiperspirant deodorant responds when you need it most so that you don't have to worry about slowing down. Simply swipe and start moving. This antiperspirant deodorant for women with a tantalizing scent gives you the confidence to keep moving all day long. Degree Clinical Protection Shower Clean Antiperspirant Deodorant keeps you feeling cool, fresh and protected from sweat and odor. Degree gives you the confidence to keep moving, however you move. At Degree, we want to inspire the confidence in everyone to move more and go further. For adult use.

Degree Clinical Protection Antiperspirant Deodorant for Women Shower Clean, 1.7 oz PRESCRIPTION-STRENGTH WETNESS PROTECTION: Active lives need Degree Clinical Protection Shower Clean Antiperspirant Deodorant. This antiperspirant delivers with 72-hour sweat and odor protection. YOU MOVE, IT WORKS: Our breakthrough MotionSense® technology works in sync with your body, all day long. This antiperspirant deodorant for women releases a burst of fragrance every time you move. READY FOR WHAT’S NEXT: Take on the day with Degree Clinical Protection Shower Clean Antiperspirant Deodorant Stick. Simply twist, glide, and move with confidence. TANTALIZING SCENT: This antiperspirant for women features the bright floral scent of rose and jasmine, blended with delicate fruit for an invigorating, clean feeling. RECYCLE WITH DEGREE: As well as increasing our use of reusable materials, we’re making it easier for you to recycle our antiperspirant and dry spray packaging. GO BEYOND YOUR LIMITS: At Degree, we want to inspire the confidence in everyone to move more and go further. We’re here to support your journey through an antiperspirant for men that moves with you. For adult use.

4. Secret Clinical Soft Solid Antiperspirant and Deodorant, Unscented Sensitive, 1.6 oz

Secret Clinical Soft Solid Antiperspirant and Deodorant, Unscented Sensitive, 1.6 oz
90%

Our Score

Secret Clinical Strength Antiperspirant and Deodorant for Women is clinically proven protection for 3 types of sweat; 1) stress sweat, 2) heat sweat and 3) activity sweat. Secret Clinical Strength offers the wetness protection of a prescription-strength product formulated to be gentle on skin, making it perfect for everyday use. Secret Clinical Strength Soft Solid-advanced protection to take on even the most stressful days. Also available in invisible solid and clear gel.

Clinical Strength protection to fight 3 types of sweat - stress, heat, and activity Clinically Proven Prescription strength wetness protection 3X* Stress Sweat Protection (*vs. the wetness protection required of an ordinary antiperspirant) Designed with female dermatologists Certified Cruelty-Free by PETA 72 HR sweat protection pH balancing minerals #1 selling clinical antiperspirant brand Secret Clinical Strength Antiperspirant and Deodorant

5. Certain Dri Clinical Strength Antiperspirant Roll-on 1.2 Oz

Certain Dri Clinical Strength Antiperspirant Roll-on 1.2 Oz
90%

Our Score

Active Ingredients: Aluminum Chloride 12% Inactive Ingredients: Sodium Bicarbonate; Water Uses: Treats excessive perspiration. Reduces underarm wetness. Doctor recommended. Prescription strength. Certain Dri contains Aluminum Chloride, the ingredient prescribed by doctors to patients with excessive perspiration or Hyperhidrosis. Laboratory studies prove that Aluminum Chloride is more effective and longer lasting than other ingredients found in anti-perspirants, yet safe when used as directed. Even after 72 hours, in an independent test, Certain Dri Prescription Strength Anti-Perspirant proved more effective and longer lasting (June 2005).

Certain Dri Clinical Strength Antiperspirant Roll-on 1.2 oz: Long-lasting protection, even after 72 hours Aluminum chloride clinical strength roll-on deodorant Helps with excessive perspiration 1.2 fl oz roll-on container More effective and longer-lasting than other antiperspirant ingredients

6. Clinical Protection Sheer Powder Anti-Perspirant by Degree for Women - 1.7 oz Deodorant Stick

Clinical Protection Sheer Powder Anti-Perspirant by Degree for Women - 1.7 oz Deodorant Stick
88%

Our Score

Degree Women Clinical Antiperspirant Deodorant Sheer Powder 1.7 oz gives strong, yet gentle protection from sweat and body odor all day long. This antiperspirant deodorant provides advanced strength wetness protection so you can stay confident to perform at your best in even the most challenging situations. For best results, apply it to your underarms before going to bed. While you rest the unique formula builds a strong level of protection from sweat and odor that lasts throughout the following day. Try pairing clinical protection with a Degree Women MotionSense Antiperspirant Deodorant stick. This deodorant contains Degree s innovative MotionSense technology to keep you fresh with every move. Degree MotionSense responds directly to your body movement, releasing extra freshness when you move. Degree MotionSense works like this unique microcapsules sit on the surface of your skin. When you move, friction breaks those microcapsules and they release more fragrance. So every time you move, MotionSense keeps you fresh and free from body odor. The more you move, the more it protects. An active life can lead to sweat and body odor. Keep moving and keep fresh all day with Degree Women. Degree Women antiperspirant deodorant gives you long lasting 48 hour protection with fresh fragrance to protect against sweat and body odor. When life demands more from you, whether you re in the gym, in the office, or out and about with friends, stay confident and dry with Degree Women. Degree. It won t let you down.

Clinical Protection Sheer Powder Anti-Perspirant by Degree for Women - 1.7 oz Deodorant Stick Model NO : W-BB-3334 Type : Deodorant Stick

7. Certain Dri Everyday Strength Clinical Antiperspirant + Deodorant, Solid, 2.6 oz

Certain Dri Everyday Strength Clinical Antiperspirant + Deodorant, Solid, 2.6 oz
88%

Our Score

Certain Dri is the #1 over-the-counter brand that doctors recommend for their patients with excessive sweating and is one of the original clinical antiperspirant brands. Certain Dri offers three levels of protection to help sufferers manage their excessive sweating. Certain Dri Everyday Strength Clinical Antiperspirant + Deodorant provides effective all day protection for more certainty against odor and sweating. With 20% Aluminum Zirconium Complex, it the first step in managing hyperhidrosis providing clinical sweat protection with added deodorant protection.

#1 DOCTOR RECOMMENDED brand for excessive sweating. CLINICAL STRENGTH antiperspirant + deodorant with 20% Aluminum Zirconium Complex in solid form. EFFECTIVE ALL DAY PROTECTION for more certainty against odor and perspiration. USAGE INSTRUCTIONS: apply at night to completely dry underarms. Can be reapplied in the morning for an extra layer of freshness and protection. CERTIFIED cruelty free by PETA.

8. Revlon Mitchum Clinical Performance Anti-Perspirant & Deodorant, 2.5 oz

Revlon Mitchum Clinical Performance Anti-Perspirant & Deodorant, 2.5 oz
86%

Our Score

Smart Solid Anti-Perspirant Unscented, Barrell 2.5 OZ Misc: Clinical performance stick. Clinically proven with maximum strength wetness protection. Clinically proven formula with the highest level of active ingredient for maximum wetness protection. Water based formula absorbs quickly, leaving no white messy residue on you or your clothes. Odorguard technology helps eliminate odor caused by bacteria to keep you feeling clean and fresh. For Male

Clinical Performance Deodorant Stick Water based formula absorbs quickly, leaving no white marks Odor Guard Technology Maximum Strength Available in Powder Scent or Unscented

9. Mitchum Smart Solid Clinical Performance Powder Anti-Perspirant & Deodorant for Women, 2.5 oz

Mitchum Smart Solid Clinical Performance Powder Anti-Perspirant & Deodorant for Women, 2.5 oz
72%

Our Score

Mitchum's most advanced formula for odor and wetness protection.

Breakthrough formula designed to banish white deodorant residue from your body and your wardrobe for good Unbeatable white residue prevention among invisible solids Patented water based formula fights sweat before it starts Antiperspirant packed with maximum level of active ingredient

10. Degree Clinical Protection Clean Anti-Perspirant & Deodorant Degree Men 1.7 oz

Degree Clinical Protection Clean Anti-Perspirant & Deodorant Degree Men 1.7 oz
0%

Our Score

Unbeatable Wetness Protection Without A Prescription Dermatologist Tested


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