The Best Frontline Plus 2025

Updated On May 2nd, 2025

Looking for the best Frontline Plus? You aren't short of choices in 2022. The difficult bit is deciding the best Frontline Plus for you, but luckily that's where we can help. Based on testing out in the field with reviews, sells etc, we've created this ranked list of the finest Frontline Plus.

Rank Product Name Score
1
Frontline Plus Dogs 23-44lb 6pk

Frontline Plus Dogs 23-44lb 6pk

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98%
2
FRONTLINE Plus for Dogs

FRONTLINE Plus for Dogs

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96%
3
Frontline Plus Dogs 89-132lb 6pk

Frontline Plus Dogs 89-132lb 6pk

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96%
4
Frontline Plus Dogs 11-22lbs 6pk

Frontline Plus Dogs 11-22lbs 6pk

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92%
5
FRONTLINE Plus Flea and Tick Treatment for Extra-Large Dogs, 6 Monthly Doses

FRONTLINE Plus Flea and Tick Treatment for Extra-Large Dogs, 6 Monthly Doses

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84%
6
Frontline Plus Orange 3 Month 11-22lb

Frontline Plus Orange 3 Month 11-22lb

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76%
7
Frontline Plus Dogs 11-22lb 3pk

Frontline Plus Dogs 11-22lb 3pk

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0%
8
FRONTLINE Plus for Dogs - Blue, 3 Month Supply

FRONTLINE Plus for Dogs - Blue, 3 Month Supply

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0%
9
Frontline Plus Dogs 45-88lb 3pk

Frontline Plus Dogs 45-88lb 3pk

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0%
10
FRONTLINE Plus for Dogs - Red, 3 Month Supply

FRONTLINE Plus for Dogs - Red, 3 Month Supply

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0%

1. Frontline Plus Dogs 23-44lb 6pk

Frontline Plus Dogs 23-44lb 6pk
98%

Our Score

short description is not available

Frontline Plus Dogs 23-44lb 6pk

2. FRONTLINE Plus for Dogs

FRONTLINE Plus for Dogs
96%

Our Score

95percent of a flea problem is in your pet's home environment as eggs, larvae and pupae (cocoons). New double action FRONTLINE Plus not only kills fleas and ticks on your pet, it contains active IGR technology that stops flea eggs from hatching and larvae developing in your home. Enhanced household protection. By preventing flea eggs from hatching, FRONTLINE Plus breaks the flea life cycle, helping to protect both the pet and the home.

FRONTLINE Plus for Dogs Apply it once and protect your pet friend for 4 week duration 0.09 fl oz capacity - Aids you keeping the pets protected all the time

3. Frontline Plus Dogs 89-132lb 6pk

Frontline Plus Dogs 89-132lb 6pk
96%

Our Score

short description is not available

Frontline Plus Dogs 89-132lb 6pk

4. Frontline Plus Dogs 11-22lbs 6pk

Frontline Plus Dogs 11-22lbs 6pk
92%

Our Score

short description is not available

Frontline Plus Dogs 11-22lbs 6pk

5. FRONTLINE Plus Flea and Tick Treatment for Extra-Large Dogs, 6 Monthly Doses

FRONTLINE Plus Flea and Tick Treatment for Extra-Large Dogs, 6 Monthly Doses
84%

Our Score

Frontline plus flea and tick prevention for large dogs 89 to 132 LBS. Kills fleas, flea eggs & larvae, ticks, and chewing lice. Kills ticks, including those that may transmit lyme disease. Frontline plus for dogs provides fast-acting, long-lasting, waterproof treatment and control of fleas, ticks, chewing lice, and sarcoptic mites for use only on dogs weighing 89-132 lbs.

6 doses. For dogs. Fast-acting. Long-lasting. Waterproof. 6-0.136 fl oz (4.02 ml) applicators. Net contents: 0.816 fl oz (24.12 ml).

6. Frontline Plus Orange 3 Month 11-22lb

Frontline Plus Orange 3 Month 11-22lb
76%

Our Score

When used monthly, Frontline Plus for Dogs & Puppies completely breaks the flea cycle and controls tick and chewing lice infestations. It kills adult fleas, flea eggs and flea larvae and prevents the development of all flea stages for up to three months.

Frontline Plus For Dogs & Puppies Flea & Tick Control: Three .023 oz applicators For dogs and puppies 8+ weeks or weighing up to 22 lbs Fast acting Waterproof

7. Frontline Plus Dogs 11-22lb 3pk

Frontline Plus Dogs 11-22lb 3pk
0%

Our Score

short description is not available

Frontline Plus Dogs 11-22lb 3pk

8. FRONTLINE Plus for Dogs - Blue, 3 Month Supply

FRONTLINE Plus for Dogs - Blue, 3 Month Supply
0%

Our Score

Frontline Plus for Dogs provides fast, effective and convenient treatment and control of fleas, ticks and chewing lice for dogs weighing 45 to 88 lbs.

Stops and prevents infestations Kills adult fleas, flea eggs & flea larvae Prevents all flea stages from developing Kills fleas of deer ticks, brown dog ticks, American dog ticks & lone star ticks Prevents and controls reinfestations Rapidly eliminates infestations with chewing lice Aids in control of sarcoptic mange infestations Can also be used on breeding, pregnant and lactating bitches Fast-acting Long-lasting Waterproof Convenient to use

9. Frontline Plus Dogs 45-88lb 3pk

Frontline Plus Dogs 45-88lb 3pk
0%

Our Score

short description is not available

Frontline Plus Dogs 45-88lb 3pk

10. FRONTLINE Plus for Dogs - Red, 3 Month Supply

FRONTLINE Plus for Dogs - Red, 3 Month Supply
0%

Our Score

FRONTLINE Plus for Dogs provides fast, effective treatment and control of fleas, ticks and lice for dogs weighing between 89 and 132 pounds.

Stops and prevents infestations Kills adult fleas, flea eggs & flea larvae Prevents all flea stages from developing Kills fleas of deer ticks, brown dog ticks, American dog ticks & lone star ticks Prevents and controls reinfestations Rapidly eliminates infestations with chewing lice Aids in control of sarcoptic mange infestations Can also be used on breeding, pregnant and lactating bitches Fast-acting Long-lasting Waterproof Convenient to use


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