The Best Headaches & Fever 2025

Updated On August 6th, 2025

Looking for the best Headaches & Fever? You aren't short of choices in 2022. The difficult bit is deciding the best Headaches & Fever for you, but luckily that's where we can help. Based on testing out in the field with reviews, sells etc, we've created this ranked list of the finest Headaches & Fever.

Rank Product Name Score
1
Lil Drug Store Products Legatrin PM Pain Reliever/Sleep Aid, 50 ea

Lil Drug Store Products Legatrin PM Pain Reliever/Sleep Aid, 50 ea

Check Price
98%
2
Bayer Aspirin Pain Reliever/ Fever Reducer, 200-Count Coated Tablets

Bayer Aspirin Pain Reliever/ Fever Reducer, 200-Count Coated Tablets

Check Price
92%
3
Bayer Low Dose Tablets 180ct

Bayer Low Dose Tablets 180ct

Check Price
0%
4
Premsyn PMS Maximum Strength 20-count

Premsyn PMS Maximum Strength 20-count

Check Price
0%
5
Advil, 250 - Caplets

Advil, 250 - Caplets

Check Price
0%
6
Bayer Tablets 100ct

Bayer Tablets 100ct

Check Price
0%
7
Midol Maximum Strength PMS Formula 24-count

Midol Maximum Strength PMS Formula 24-count

Check Price
0%
8
Excedrin Extra Strength, 100 - Tablets

Excedrin Extra Strength, 100 - Tablets

Check Price
0%
9
Excedrin Migraine 100-count

Excedrin Migraine 100-count

Check Price
0%
10
Excedrin Extra Strength, 275 - Tablets

Excedrin Extra Strength, 275 - Tablets

Check Price
0%

1. Lil Drug Store Products Legatrin PM Pain Reliever/Sleep Aid, 50 ea

Lil Drug Store Products Legatrin PM Pain Reliever/Sleep Aid, 50 ea
98%

Our Score

Pain Relief, Legatrin PM, Acetaminophen, Diphenhydramine HCI, Caplets, Box 50 CT Other Information: Store at controlled room temperature 68 degrees to 77 degrees F (20 degrees to 25 degrees C). Avoid excessive heat and humidity. Tamper Evident. Do not e if carton is opened or neck wrap or foil inner seal is broken. See end panel for lot number and expiration date. Misc: Contains acetaminophen, diphenhydramine HCl. Relieves lower body pain, including leg cramp pain. Safe, non-habit forming. Jt 1 caplet helps you sleep! Leg cramp pain. Joint pain. Lower backache. Sore feet. www.legatrinpm.com. Questions or comments? 1-877-507-6516 (M-F 8 AM-4:30 PM CST) or www.legatrinpm.com. . es: Temporary relief of minor aches and pains, such as leg cramp pain, joint pain, lower backache, and sore feet, with accompanying sleeplessness. Directions: Do not exceed recommended dosage. Adults and Children 12 Years of Age and Older: 1 caplet at bedtime as needed, or as directed by a doctor. Children Under 12 Years: Consult a doctor. Warnings: Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours; with other drugs containing acetaminophen; 3 or more alcoholic drinks every day while ing this product. Do not e: with any other drug containing acetaminophen (prescription or nonprescription) (If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist); with any other product containing diphenhydramine, even one ed on skin; in children under 12 years of age. Ask a doctor before e if you have liver disease; glaucoma; breathing problem such as asthma, emphysema, chronic bronchitis or pulmonary disease; trouble urinating due to an enlarged prostate gland; heart disease; high blood pressure; thyroid disease; diabetes. Ask a doctor or pharmacist before e if you are taking tranquilizers or sedatives; taking the blood thinning drug warfarin. When ing this product: drowsiness will occur; do not drive a motor vehicle or operate machinery; avoid alcoholic drinks. Stop e and ask a doctor if: sleeplessness persists continuoly for more than 2 weeks (Insomnia may be a symptom of serio underlying medical illness); pain gets worse or lasts for more than 10 days; fever gets worse or lasts for more than 3 days; symptoms do not improve within 7 days or are accompanied by a fever; new symptoms occur; redness or swelling is present; nervoness, dizziness or sleeplessness occur. Pregnancy/breast-feeding warning: If pregnant or breast-feeding, ask a health professional before e. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms. Other warnings: Do not e if neck wrap or foil inner seal is broken. 50 caplets 1201 Continental Place NE Cedar Rapids, IA 52402 877-507-6516

Pain Reliever/Sleep Aid, Caplets Other Information: Store at controlled room temperature 68 degrees to 77 degrees F (20 degrees to 25 degrees C). Avoid excessive heat and humidity. Tamper Evident. Do not e if carton is opened or neck wrap or foil inner seal is broken. See end panel for lot number and expiration date. Misc: Contains acetaminophen, diphenhydramine HCl. Relieves lower body pain, including leg cramp pain. Safe, non-habit forming. Jt 1 caplet helps you sleep! Leg cramp pain. Joint pain. Lower backache. Sore feet. www.legatrinpm.com. Questions or comments? 1-877-507-6516 (M-F 8 AM-4:30 PM CST) or www.legatrinpm.com. .

2. Bayer Aspirin Pain Reliever/ Fever Reducer, 200-Count Coated Tablets

Bayer Aspirin Pain Reliever/ Fever Reducer, 200-Count Coated Tablets
92%

Our Score

he package pretty much says it all: Genuine Bayer. What else do you really need? Sure, your grandparents used Bayer, and your parents used Bayer. But that's no reason for you not to use Bayer. Bayer aspirin has been present on medicine cabinet shelves for years because it gives reliable fever and pain relief at an old-fashioned price. There are more voguish pain relievers on the market, but genuine Bayer is all you really need.

Bayer Aspirin Pain Reliever 325Mg - 200 Tablets: There are more voguish pain relievers on the market, but genuine Bayer is all you really need. Original strength aspirin pain reliever Fast, safe pain relief; reduces fever Coated for easier swallowing 200 tablets, 325 mg each Please read all label information on delivery

3. Bayer Low Dose Tablets 180ct

Bayer Low Dose Tablets 180ct
0%

Our Score

short description is not available

Safety coated caplets, delayed released aspirin, 81mg, 180 caplets

4. Premsyn PMS Maximum Strength 20-count

Premsyn PMS Maximum Strength 20-count
0%

Our Score

Helps relieve symptoms of premenstrual syndrome including tension, bloating, cramps, headache, backache and water weight gain. Features: Aspirin-free Caffeine-free 20 Count

Relief for the period before your period.

5. Advil, 250 - Caplets

Advil, 250 - Caplets
0%

Our Score

Advanced medicine for pain. Contains ibuprofen, a safe and effective pain reliever which has been prescribed by doctors for millions. Now available in non-prescription strength.

Use Advil for the temporary relief of minor aches and pains associated with: Common cold Headaches Toothaches Muscular aches Backaches Minor pain of arthritis Menstrual cramps

6. Bayer Tablets 100ct

Bayer Tablets 100ct
0%

Our Score

short description is not available

Bayer Tablets 100ct

7. Midol Maximum Strength PMS Formula 24-count

Midol Maximum Strength PMS Formula 24-count
0%

Our Score

Relief of the symptoms of premenstrual syndrome so you can feel yourself again.

Relief of the symptoms of premenstrual syndrome so you can feel yourself again.

8. Excedrin Extra Strength, 100 - Tablets

Excedrin Extra Strength, 100 - Tablets
0%

Our Score

Excedrin Extra Strength is a combination pain reliever designed to kick even the toughest headache.

Contains acetaminophen, aspirin and caffeine Easy-to-swallow coated tablets

9. Excedrin Migraine 100-count

Excedrin Migraine 100-count
0%

Our Score

Approved for the relief of mild or moderate migraine headaches.

Approved for the relief of mild or moderate migraine headaches.

10. Excedrin Extra Strength, 275 - Tablets

Excedrin Extra Strength, 275 - Tablets
0%

Our Score

Excedrin Extra Strength is a combination pain reliever designed to kick even the toughest headache.

Contains acetaminophen, aspirin and caffeine Easy-to-swallow coated tablets


arrow_upward